Research on the interaction between the body’s gut microbiome and overall health has shown that a healthy gut microbiome and certain foods are linked to better cardiovascular health. Previous studies have connected a healthy gut microbiome with cholesterol metabolism, which plays a role in heart disease. Additionally, consuming specific foods like blueberries, legumes, chia seeds, and leafy greens has been shown to improve cardiovascular health. A new study published in the Journal of Agricultural and Food Chemistry examined the potential of an extract made from orange peels to improve heart health by inhibiting the production of trimethylamine N-oxide (TMAO), a compound linked to cardiovascular disease.
The extract from orange peels was found to contain certain chemicals that can inhibit the production of harmful chemicals in the cardiovascular system. The researchers focused on TMAO, which is produced by gut bacteria feeding on certain nutrients found in red meat and dairy products. By reducing the amount of TMAO produced in the gut microbiome, the researchers hoped to improve heart health. The study tested two types of orange peel extracts, one with a polar fraction and the other with a non-polar fraction. The non-polar fraction orange peel extract was able to stop the production of TMAO in male mice, while the polar fraction contained a compound that inhibited the enzyme responsible for producing TMA, a precursor to TMAO.
The study’s findings open up new possibilities for improving heart health through dietary interventions that target the gut microbiome. By understanding how the gut microbiome processes foods to produce beneficial compounds, researchers may be able to identify new ways to reduce the risk of cardiovascular disease. Citrus fruits like oranges are rich in antioxidants, polyphenols, vitamin C, potassium, and fiber, all of which are associated with a lowered risk of heart disease. Incorporating citrus fruits and their peels into the diet can support gut health, which in turn benefits heart health by promoting the growth of beneficial bacteria and aiding in the removal of harmful compounds like TMAO.
However, it is important to note that orange peel extract and orange juice can interact with certain medications, including statins, antibiotics, anti-parasitics, and beta-blockers. Furthermore, orange peels can be bitter, contain pesticide residue, and may cause digestive issues if not consumed carefully. To incorporate orange peels into the diet, readers are advised to use organic, thoroughly washed peels in cooking, teas, smoothies, and other dishes. By adding a variety of citrus fruits to their diet, individuals can not only improve gut and heart health but also enjoy the vibrant tastes and smells of these fruits. Overall, the study highlights the potential benefits of citrus fruits and their peels for promoting heart health through interactions with the gut microbiome.
