Scientists have identified a new class of COVID subvariants called FLiRT, which has quickly spread through the U.S. One strain, KP.2, has become the dominant strain of coronavirus in the U.S. as of May 11, according to the U.S. Centers for Disease Control and Prevention. These subvariants are more infectious than previous strains due to mutations in the spike protein that help the virus evade the immune system. Despite these differences, current vaccines are still expected to provide some level of immunity against these new strains, although a new vaccine based on JN.1 or one of the FLiRT subvariants is expected to provide better protection.
Even though the FLiRT subvariants are genetically distant from the current vaccine, it is believed that the vaccine will still provide some cross-immunity against them. Experts agree that while the existing vaccines may not be a perfect match for the new variants, they are likely to offer some level of protection. A new vaccine based on the FLiRT subvariants is expected to be available around September, providing improved protection. As the new FLiRT subvariants have only been reported recently, the severity of these variants may change, but it is anticipated that they will lead to increased transmission, case numbers, hospitalizations, and deaths, though not as high as in earlier waves.
Most adults infected with the new variants experience flu-like symptoms and recover within a few days. However, there is concern about the potential for long COVID, particularly after repeated infections. Vulnerable individuals, such as the elderly or those with underlying health conditions, are at risk of severe illness and should stay up to date with booster shots, wear N95/P2 masks in public places, and have a plan in place with their healthcare provider for quick access to antivirals if needed. It is important for those who develop respiratory infections to stay at home to avoid spreading the illness to others.
In conclusion, the emergence of the FLiRT subvariants raises concerns about a potential “summer wave” of COVID-19 infections in the U.S. These variants are more infectious and may lead to increased transmission, but current vaccines are still expected to offer some level of immunity. A new vaccine based on the FLiRT subvariants is anticipated to provide improved protection. Vulnerable individuals should take precautions to protect themselves from serious illness, and it is important for everyone to stay informed and follow public health guidelines to help prevent the spread of COVID-19.
