Sugar substitutes have been around since 1879, with sugar alcohols like erythritol being one of the latest types. Previous research has linked erythritol to cardiovascular issues such as heart attack and stroke. A study published in March 2023 found an association between erythritol use and an increased risk for major cardiovascular events. A new study published in the journal Arteriosclerosis, Thrombosis and Vascular Biology reports that erythritol use may also increase a person’s risk of blood clots, which can restrict the movement of blood and oxygen around the body. Healthy volunteers who consumed erythritol experienced an increase in blood platelet activity, raising their risk of blood clot formation. Every subject showed an increase in clotting potential after drinking erythritol, with no change observed after consuming glucose.
Stanley L. Hazen, MD, PhD, and his colleagues have conducted research on the effects of erythritol, with findings suggesting an increase in blood clotting potential. The study involved 20 healthy volunteers who were given water mixed with either erythritol or glucose. Participants who received erythritol experienced a significant increase in blood platelet activity, indicating a higher risk of blood clot formation. Hazen emphasized that individuals at risk of thrombosis, such as those with heart disease, diabetes, or metabolic syndrome, may want to limit their consumption of sugar alcohols. He also highlighted the need for further long-term clinical studies to assess the safety of erythritol and other sugar substitutes.
Yu-Ming Ni, MD, a board-certified cardiologist, expressed concern about the relationship between erythritol and blood clots, emphasizing the potential risks associated with sugar substitutes. Monique Richard, MS, RDN, LDN, a registered dietitian nutritionist, echoed these concerns, emphasizing the importance of mindful assessment of sugar substitutes and sugar intake. Richard advised readers to seek guidance from qualified health professionals and learn how to read labels to understand the types and definitions of sugar substitutes. She recommended using natural options like stevia and monk fruit for sweetening recipes and meals, while still consuming natural or minimally refined sugars in moderation as part of a healthy diet.
In light of the risks associated with erythritol and other sugar substitutes, individuals are advised to be mindful of their consumption and consider natural sweetener options. The study conducted by Hazen and his team highlights the potential health concerns related to erythritol ingestion, particularly for individuals at risk of cardiovascular issues and blood clot formation. Further research is needed to fully understand the effects of sugar alcohols on health and to determine the appropriate limits for consumption, especially for individuals with preexisting conditions. It is important for individuals to educate themselves about sugar substitutes and make informed choices about their dietary habits to promote overall health and well-being.
