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John and Ali Shadock had only been married a few years when John began experiencing severe headaches at the age of 35. The headaches were excruciating and persistent, prompting a visit to the doctor. A brain scan revealed a large tumor, later identified as glioblastoma, a complex and deadly form of cancer. Despite the grim prognosis of an average survival of eight months, John has been doing well more than five years after his diagnosis, defying the odds.

Glioblastoma can affect anyone at any age, though it is more common in older individuals. The exact cause of this aggressive cancer remains unknown, making treatment challenging. Standard treatment involves surgery to remove as much of the tumor as possible, followed by radiation and chemotherapy. Clinical trials for new therapies are crucial in extending the lifespan of patients with glioblastoma, as traditional approaches often only provide a few additional months of life.

John Shadock participated in clinical trials involving immunotherapy approaches, including the infusion of a modified polio virus to stimulate his immune system’s response to the cancer cells. His body’s unique ability to fight the cancer and the positive support from his family, particularly his wife Ali, have contributed to his remarkable survival. His fitness level at the time of diagnosis and proactive mindset have also played a role in his resilience against glioblastoma.

Ali Shadock has been a dedicated advocate for her husband, attending all his medical appointments and celebrating every bit of progress. She emphasizes the importance of staying proactive and exploring all possible options and treatments. Despite facing significant medical debt and the challenges of caregiving, the couple remains grateful for the opportunity to continue living and fighting against the disease.

The Shadocks’ journey with glioblastoma has been marked by remarkable resilience and strength. Ali’s unwavering positivity and determination, coupled with John’s physical fitness and involvement in clinical trials, have defied the grim statistics associated with the disease. Their Instagram page, “Strong All Along,” reflects their motto of facing challenges head-on and finding hope and options even in the face of a dire diagnosis.

Glioblastoma Awareness Day on July 17, 2024, serves as a reminder of the thousands of individuals diagnosed with this aggressive cancer each year. While there is currently no cure for glioblastoma, advancements in research and clinical trials offer hope for improved treatment options and prolonged survival. The Shadocks’ story is a testament to the power of love, determination, and resilience in the face of adversity, inspiring others to remain hopeful and proactive in their fight against cancer.

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